AGGREGATION

Pronunție (USA): (GB):

Traducere în limba română

aggregation substantiv

1. strângere, adunare, reunire.

2. (chim.) agregare, stare de agregaţie; (tehn.) agregat.

3. masă, conglomerat.

4. putere de coeziune.

Exemple de propoziții și/sau fraze:

Any process which promotes degranulation of platelets and release of platelet-activating factor into the plasma, resulting in signaling through the G protein-coupled platelet-activating factor receptor and aggregation of platelets.

(Platelet Activating Factor Signaling Process, NCI Thesaurus)

This gene plays a role in signal transduction, angiogenesis and platelet aggregation.

(NOS3 Gene, NCI Thesaurus)

The gene is also involved in cellular proliferation and aggregation.

(AXL Gene, NCI Thesaurus)

Alzheimer's disease is associated with dense aggregations of proteins in the brain called amyloid plaques that contain beta-amyloid fragments as a primary component.

(Amyloid Beta-Peptide Pathway, NCI Thesaurus/BIOCARTA)

Calcium release induced by PARs activates PKC, modulating integrin alpha IIB beta 3 (glycoprotein IIb/IIIa) and opening integrin ligand binding sites to contribute to platelet aggregation.

(Aspirin Inhibition of Platelet Activation Pathway, NCI Thesaurus/BIOCARTA)

This agent also causes a decrease in the formation of thromboxane A2 synthesis by thromboxane synthase, thereby inhibiting platelet aggregation.

(Aspirin DL-Lysine, NCI Thesaurus)

Inhibition of LTD4 activity results in inhibition of leukotriene-mediated inflammatory events including: migration of eosinophils and neutrophils; adhesion of leukocytes to vascular endothelium, monocyte and neutrophil aggregation; increased airway edema; increased capillary permeability; and bronchoconstriction.

(Montelukast sodium, NCI Thesaurus)

This agent may activate the NO/cyclic GMP pathway and inhibit both the phospholipase C gamma 2 (PLC gamma2)/protein kinase C (PKC) and PI3K/AKT-MAPK signaling pathways in activated platelets to inhibit platelet aggregation.

(Andrographolide, NCI Thesaurus)

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