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BLOCKING

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blocking substantiv

blocare etc. (v. block II).

 Exemple de propoziții și/sau fraze: 

Anti-HB-EGF Monoclonal Antibody KHK2866 binds to HBEGF, thereby blocking its binding to the EGF receptors.

(Anti-HB-EGF Monoclonal Antibody KHK2866, NCI Thesaurus)

Anakinra binds to the IL-1 receptor, thereby blocking the binding of the IL-1 to and activation of its receptor.

(Anakinra, NCI Thesaurus)

Upon intravenous administration, MEDI4736 binds to the cell surface antigen B7H1, thereby blocking B7H1 signaling.

(Anti-B7H1 Monoclonal Antibody MEDI4736, NCI Thesaurus)

Upon administration, anti-c-fms monoclonal antibody AMG 820 binds to and blocks c-fms, thereby blocking CSF-1 binding to its receptor and suppressing CSF-1-induced c-fms signaling.

(Anti-c-fms Monoclonal Antibody AMG 820, NCI Thesaurus)

Norfloxacin inhibits activity of DNA gyrase, thereby blocking bacterial DNA replication.

(Norfloxacin, NCI Thesaurus)

Anti-CD200 monoclonal antibody ALXN6000 binds to CD200, blocking the binding of CD200 to its receptor, CD200R, present on cells of the macrophage lineage; inhibition of CD200 may augment the cytotoxic T-lymphocyte (CTL) mediated immune response against CD200-expressing tumor cells.

(Anti-CD200 Monoclonal Antibody ALXN6000, NCI Thesaurus)

Scientists think that blocking the phosphorylation of s15 ribosomal proteins could lead to future therapies as might other strategies which decrease bulk protein synthesis or increase the cells’ ability to cope with increased protein metabolism.

(Too much protein may kill brain cells as Parkinson’s progresses, NINDS)

As a folate analogue, aminopterin competes for the folate binding site of the enzyme dihydrofolate reductase, thereby blocking tetrahydrofolate synthesis, and resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis.

(Aminopterin, NCI Thesaurus)

The telescope's camera detected a periodic dimming of the light emitted by the planet's host star, a sign that an orbiting planet could be regularly passing in front of the star and blocking the light.

(NASA's K2 Finds Newborn Exoplanet Around Young Star, NASA)

This agent also induces apoptosis by both binding to and blocking the function of the apoptosis inhibitor protein B-cell Leukemia 2 (Bcl-2).The mucoadhesive paclitaxel formulation does not contain P-glycoprotein inhibitors, the solvent cremophor or any other toxic solvent.

(Mucoadhesive Paclitaxel Formulation, NCI Thesaurus)




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