COMPETE

Pronunție (USA): (GB):

Traducere în limba română

compete verb intranzitiv

(with; for) a se lua la întrecere, a concura, a fi / a intra în competiţie / în concurenţă / în încercare (cu, pentru).

Exemple de propoziții și/sau fraze:

This agent also competes with free serotonin for binding at serotonin receptor sites.

(Cyproheptadine Hydrochloride, NCI Thesaurus)

It was one thing to fight as you and I have fought in our youth, and it was another to compete for a purse of gold.

(Rodney Stone, de Sir Arthur Conan Doyle)

Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor subtype in vascular smooth muscle and adrenal gland, thereby competing with angiotensin II for binding to the AT1 receptor.

(Olmesartan, NCI Thesaurus)

He shall not compete.

(The Return of Sherlock Holmes, de Sir Arthur Conan Doyle)

As an analog of arginine, amino-arginine competes with the normal substrate arginine and binds to the heme of the NOS as a false substrate, thereby inhibiting endothelial and inducible nitric oxide synthases (eNOS / NOS III and iNOS / NOS II).

(Amino-Arginine, NCI Thesaurus)

Antibody 225 competes with EGF or transforming growth factor-alpha (TGF alpha) for receptor binding and thereby prevents ligand-induced receptor tyrosine kinase activation resulting in the inhibition of proliferation of human cancer cells that are stimulated by the TGFalpha/EGF receptor autocrine loop.

(Murine Monoclonal Antibody 225, NCI Thesaurus)

After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with angiotensin II for the binding of the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation.

(Candesartan Cilexetil, NCI Thesaurus)

As a folate analogue, aminopterin competes for the folate binding site of the enzyme dihydrofolate reductase, thereby blocking tetrahydrofolate synthesis, and resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis.

(Aminopterin, NCI Thesaurus)

Selectively active against tumor cells expressing high levels of thymidylate synthase (TS), brivudine is converted intracellularly by TS to bromovinyldeoxyuridine monophosphate (BVdUMP) which competes with the natural substrate, deoxyuridine monophosphate, for binding to TS.

(Brivudine Phosphoramidate, NCI Thesaurus)

JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and so the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells.

(Momelotinib, NCI Thesaurus)

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