CONJUGATE

Pronunție (USA): (GB):

Traducere în limba română

conjugate I. verb A. tranzitiv

(gram.) a conjuga.

conjugate I. verb B. intranzitiv

(biol.) a se împreuna, a se însoţi, a se împerechea.

conjugate II. adjectiv

1. împreunat, unit, cuplat; conjugat, îmbinat, combinat; (fiz., fiziol.) conjugat.

2. (bot. despre fructe) împerecheat.

3. (lingv. despre cuvinte) cu aceeaşi rădăcină.

4. (biol.) contopit, fuzionat.

conjugate III. substantiv

(lingv.) derivat, cuvânt cu aceeaşi rădăcină.

Exemple de propoziții și/sau fraze:

Anti-CD19-DM4 conjugate SAR3419 targets the cell surface antigen CD19, found on a number of B-cell-derived cancers.

(Anti-CD19-DM4 Immunoconjugate SAR3419, NCI Thesaurus)

The monoclonal antibody portion of the anti-CD33 monoclonal antibody-drug conjugate SGN-CD33A specifically binds to the cell surface antigen CD33.

(Anti-CD33 Antibody-Drug Conjugate SGN-CD33A, NCI Thesaurus)

An immunoconjugate consisting of a humanized monoclonal antibody against the tumor-associated sialoglycotope CA6 (huDS6) conjugated to the cytotoxic maytansinoid DM4, with potential antineoplastic activity.

(Anti-CA6-DM4 Immunoconjugate SAR566658, NCI Thesaurus)

Adcetris is a type of antibody-drug conjugate.

(Adcetris, NCI Dictionary)

Ado-trastuzumab emtansine is a type of antibody-drug conjugate.

(Ado-trastuzumab emtansine, NCI Dictionary)

An immunoconjugate consisting of the humanized monoclonal antibody huMy9-6 conjugated to the cytotoxic maytansinoid DM4 with potential antineoplastic activity.

(Anti-CD33 Monoclonal Antibody-DM4 Conjugate AVE9633, NCI Thesaurus)

An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody, directed against the extracellular domain of the human CD70 molecule, conjugated to a prodrug of a CC-1065 (rachelmycin) analogue via a stable peptide-based linker, with potential antineoplastic activity.

(Anti-CD70 Antibody-Drug Conjugate MDX-1203, NCI Thesaurus)

By binding to proteoglycan chondroitin sulfate-associated protein, monoclonal antibody Me1-14 F(ab')2 conjugated to a radioisotope may localize gliomas and melanomas when used as a tracer in radioimaging applications; in radioimmunotherapeutic applications, this agent conjugated to a radioisotope may be used to deliver targeted radiotoxicity to these tumors.

(Monoclonal Antibody Me1-14 F(ab')2, NCI Thesaurus)

Upon administration of a biotin-based radioconjugate, the biotin moiety of the radioconjugate binds to the streptavidin moiety of anti-CD45 BC8 antibody-streptavidin conjugate and, upon cellular internalization, specifically delivers cytotoxic radiation to CD45-expressing tumor cells.

(Anti-CD45 BC8 Monoclonal Antibody-Streptavidin Conjugate, NCI Thesaurus)

An immunoconjugate consisting of a humanized monoclonal antibody that is engineered to contain cysteine residues that are conjugated to the synthetic, DNA cross-linking, pyrrolobenzodiazepine dimer SGD-1882, via the protease-cleavable linker maleimidocaproyl-valine-alanine dipeptide, with potential antineoplastic activity.

(Anti-CD33 Antibody-Drug Conjugate SGN-CD33A, NCI Thesaurus)

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