DEPLETE

Pronunție (USA): (GB):

Traducere în limba română

deplete verb tranzitiv

1. a goli, a termina, a istovi, a epuiza (rezerve, stocuri, provizii); a degrada.

2. a curăţa, a uşura (intestinele).

3. (med.) a descongestiona (sistemul sanguin).

Exemple de propoziții și/sau fraze:

By depleting cells of glutathione, this agent may enhance the in vitro and in vivo cytotoxicities of various chemotherapeutic agents in drug-resistant tumors.

(Buthionine sulfoximine, NCI Thesaurus)

A molecular genetic technique that depletes a biological sample of nucleosomal DNA and then subjects the non-nucleosome-associated DNA to next-generation sequencing.

(FAIRE-Seq, NCI Thesaurus)

Anti-CD19 monoclonal antibody XmAb5574 targets and binds to CD19, thereby depleting and eliminating CD19-expressing B-cells.

(Anti-CD19 Monoclonal Antibody XmAb5574, NCI Thesaurus)

These microbes then endanger corals by depleting oxygen from the environment or by introducing diseases.

(Too much algae and too many microbes threaten coral reefs, NSF)

Upon intravenous administration of pegylated recombinant human arginase I BCT-100, arginase metabolizes the amino acid arginine to ornithine and urea, depleting intracellular arginine, which may inhibit proliferation of cells that are auxotrophic for arginine such as hepatocellular carcinoma (HCC) cells.

(Pegylated Recombinant Human Arginase I BCT-100, NCI Thesaurus)

As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells.

(N-Methylformamide, NCI Thesaurus)

New research on solar storms finds that they not only can cause regions of excessive electrical charge in the upper atmosphere above Earth's poles, they also can do the exact opposite: cause regions that are nearly depleted of electrically charged particles.

(Solar Storms Can Drain Electrical Charge Above Earth, NASA)

What we found using different tumor models is that if you treat mice with antibiotics and thereby deplete certain bacteria, you can change the composition of immune cells of the liver, affecting tumor growth in the liver, said Tim Greten, M.D., of NCI’s CCR, who led the study.

(Study finds gut microbiome can control antitumor immune function in liver, National Institutes of Health)

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