Dicţionar englez-român |
FRAGMENTATION
Pronunție (USA): | (GB): |
Traducere în limba română
fragmentation substantiv
fragmentare, îmbucătăţire, rupere în bucăţi.
Exemple de propoziții și/sau fraze:
Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic factors, activation of caspases, and DNA fragmentation.
(Betulinic Acid, NCI Thesaurus)
In addition, in vitro MeSeCys has been shown to potentiate the antitumor effects of the irinotecan metabolite SN-38, by inducing phosphorylation of checkpoint kinase 2 (chk2) at threonine 68, which results in poly(ADP-ribose) polymerase cleavage, caspase 3 activation, and DNA fragmentation.
(high-selenium Brassica juncea, NCI Thesaurus)
Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.
(Deoxycytidine Analogue TAS-109, NCI Thesaurus)