HUMANIZE

Pronunție (USA): (GB):

Traducere în limba română

humanize verb A. tranzitiv

a umaniza;

to humanize cow’s milk a asimila laptele de vacă cu laptele omenesc (pentru copii).

humanize verb B. intranzitiv

a se umaniza, a deveni omenos.

Exemple de propoziții și/sau fraze:

A humanized monoclonal antibody targeting glycolipids, with potential immunomodulating and antineoplastic activity.

(Monoclonal Antibody CEP-37250/KHK2804, NCI Thesaurus)

An immunoconjugate consisting of a humanized monoclonal antibody against the tumor-associated sialoglycotope CA6 (huDS6) conjugated to the cytotoxic maytansinoid DM4, with potential antineoplastic activity.

(Anti-CA6-DM4 Immunoconjugate SAR566658, NCI Thesaurus)

An immunoconjugate consisting of the humanized monoclonal antibody huMy9-6 conjugated to the cytotoxic maytansinoid DM4 with potential antineoplastic activity.

(Anti-CD33 Monoclonal Antibody-DM4 Conjugate AVE9633, NCI Thesaurus)

A humanized IgG1 monoclonal antibody against CD123 (Interleukin-3 receptor alpha chain or IL3RA) with potential antineoplastic activity.

(Anti-CD123 Monoclonal Antibody CSL362, NCI Thesaurus)

A humanized monoclonal antibody directed against the activator of g-proteins signaling (AGS) cell surface protein AGS-8 with potential antineoplastic activity.

(Anti-AGS-8 Monoclonal Antibody AGS-8M4, NCI Thesaurus)

A humanized monoclonal antibody directed against the activator of g-proteins signaling (AGS) cell surface protein AGS-16 with potential antineoplastic activity.

(Anti-AGS-16 Monoclonal Antibody AGS-16M18, NCI Thesaurus)

A humanized monoclonal antibody directed against the human immunosuppressive molecule CD200 (OX-2) with potential immunomodulating and antineoplastic activities.

(Anti-CD200 Monoclonal Antibody ALXN6000, NCI Thesaurus)

A glycoengineered, humanized IgG1 monoclonal antibody with potential antineoplastic activity.

(Obinutuzumab, NCI Thesaurus)

Anti-CTLA4 MoAb RNA/GITRL RNA-transfected DC vaccine is prepared by transfecting DCs with RNAs encoding humanized heavy and light chains of the anti-CTLA4 (cytotoxic T-Lymphocyte-Associated Antigen 4) monoclonal antibody and tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18 or GlTRL); expression of anti-CTLA4 blocks the inhibitory effect of CTLA4 on the activation of T-lymphocytes, while expression of GlTRL modulates T lymphocyte survival in peripheral tissues.

(Anti-CTLA4 MoAb RNA/GITRL RNA-transfected Autologous Dendritic Cell Vaccine, NCI Thesaurus)

The proprietary humanized catalytic IgG1 monoclonal aldolase antibody contains reactive lysine residues in its binding sites, which react covalently with compounds having a diketone function; the Ang2 and VEGFR peptide moieties are then covalently attached to the diketone linkers via a proprietary spacer.

(Ang2/VEGF-Binding Peptides-Antibody Fusion Protein CVX-241, NCI Thesaurus)

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