IMPEDE

Pronunție (USA): (GB):

Traducere în limba română

impede verb tranzitiv

a împiedica, a opri; a stânjeni, a deranja, a jena; a întârzia, a reţine.

Exemple de propoziții și/sau fraze:

Anti-Notch receptor monoclonal antibody OMP-59R5 binds to Notch on the cell surface, thereby inhibiting Notch-mediated signaling and gene transcription, which may impede tumor angiogenesis.

(Anti-Notch Receptor Monoclonal Antibody OMP-59R5, NCI Thesaurus)

A capsule composed of active and/or inert ingredient(s) small, spherical structures that have been coated with a substance that is designed to impede the immediate release of the active and/or inert ingredient(s) after administration.

(Delayed Release Pellet in Capsule Dosage Form, NCI Thesaurus)

Anthracycline analogue GPX-150 intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis.

(Anthracycline Analogue GPX-150, NCI Thesaurus)

Although the exact relationship between DNA binding and its activity has yet to be fully elucidated, amsacrine intercalates DNA through its acridine moiety, and its nonintercalative headgroup impedes topoisomerase II activity, augmenting enzyme-mediated DNA cleavage and resulting in DNA double-strand breaks.

(Amsacrine Lactate, NCI Thesaurus)

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