INFLAMMATORY

Pronunție (USA): (GB):

Traducere în limba română

inflammatory adjectiv

1. (fig.) aţâţător, incendiar.

2. (med.) inflamator.

Exemple de propoziții și/sau fraze:

Inhibition of LTD4 activity results in inhibition of leukotriene-mediated inflammatory events including: migration of eosinophils and neutrophils; adhesion of leukocytes to vascular endothelium, monocyte and neutrophil aggregation; increased airway edema; increased capillary permeability; and bronchoconstriction.

(Montelukast sodium, NCI Thesaurus)

An orally bioavailable small-molecule inhibitor of p38 and Tie2 kinases with potential antineoplastic, anti-inflammatory and antiangiogenic activities. p38/Tie2 kinase inhibitor Arry-614 binds to and inhibits the activities of p38 and Tie2 kinases, which may inhibit the production of proinflammatory cytokines and may decrease tumor angiogenesis and tumor cell growth and survival. p38 is a MAP kinase that is often upregulated in cancer cells, playing a crucial part in the production of a variety of cytokines involved in inflammation and cellular proliferation such as tumor necrosis factor (TNF) and interleukin (IL)-1 and -6.

(Multikinase Inhibitor ARRY614, NCI Thesaurus)

This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.. Specifically, mometasone furoate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2.

(Mometasone furoate, NCI Thesaurus)

Like other NSAIDs (non-steroidal anti-inflammatory drugs), acetaminophen has a unique activity profile based in part on its action at its molecular targets, the cyclooxygenase enzymes that produce prostaglandins responsible for pain, fever and inflammation.

(Acetaminophen Pathway, NCI Thesaurus/BIOCARTA)

Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (e.g., carcinomatous meningitis), and other inflammatory conditions may produce this syndrome.

(Meningitis, NLM, Medical Subject Headings)

Given their finding that PHD proteins suppress the inflammatory immune response in the lung, the researchers wondered whether inhibiting them might improve the efficacy of adoptive cell transfer, a type of immunotherapy that harnesses the ability of a patient’s own T cells to recognize and attack cancer.

(Oxygen can impair cancer immunotherapy in mice, NIH)

Adenosine receptor A2a (412 aa, 45 kD) is a cell defense response protein that is encoded by the human ADORA2A gene and has roles in G protein-coupled cell-cell signaling, cellular defense response, phagocytosis, blood circulation, inflammatory response, sensory perception and central nervous system development.

(Adenosine Receptor A2a, NCI Thesaurus)

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