INHIBITION

Pronunție (USA): (GB):

Traducere în limba română

inhibition substantiv

1. (jur.) oprire, interzicere, interdicţie; (bis.) caterisire (a unui preot); (mar., com.) sechestru, poprire (pe un vas); interzicerea comerţului pe mare.

2. (from) oprire, reţinere, împiedicare, înfrânare (de la).

3. (fiziol.) inhibare, inhibiţie.

4. (med.) inhibition of blood absorbţie de sânge.

Exemple de propoziții și/sau fraze:

This may result in cell growth inhibition in tumors that overexpress c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in a variety of cancers, plays an important role in tumor cell proliferation, survival, invasion, metastasis and tumor angiogenesis.

(MET Tyrosine Kinase Inhibitor SAR125844, NCI Thesaurus)

MET tyrosine kinase inhibitor PF-04217903 selectively binds to and inhibits c-Met, disrupting the c-Met signaling pathway, which may result in the inhibition of tumor cell growth, migration and invasion of tumor cells, and the induction of death in tumor cells expressing c-Met.

(MET Tyrosine Kinase Inhibitor PF-04217903, NCI Thesaurus)

IL-12 expressed by the adenovirus may activate the immune system by promoting the activation of natural killer cells, inducing the secretion of interferon-gamma and inducing a cytotoxic T lymphocyte response against tumor cells, which may result in immune-mediated tumor cell death and inhibition of tumor cell proliferation.

(Adenoviral Transduced hIL-12-expressing Autologous Dendritic Cells INXN-3001 Plus Activator Ligand INXN-1001, NCI Thesaurus)

Upon administration, adenovirus encoding rat HER-2/neu may induce an immune response against tumor cells expressing the HER-2/neu antigen, which may result in the immune-mediated inhibition of tumor cell proliferation and tumor cell death.

(Adenovirus Encoding Rat HER-2/neu, NCI Thesaurus)

MEK1/2 inhibitor AS703988/MSC2015103B selectively binds to and inhibits the activity of MEK1/2, preventing the activation of MEK1/2-dependent effector proteins and transcription factors, which may result in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation.

(MEK 1/2 Inhibitor AS703988/MSC2015103B, NCI Thesaurus)

Abexinostat inhibits several isoforms of HDAC, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; and the tumor suppressor protein-mediated inhibition of tumor cell division and induction of tumor cell apoptosis.

(Abexinostat, NCI Thesaurus)

MEK inhibitor WX-554 selectively binds to and inhibits the activity of MEK, thereby preventing the activation of MEK-dependent effector proteins including some transcription factors, which may result in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation.

(MEK Inhibitor WX-554, NCI Thesaurus)

Vaccination with Ad5F35-LMP1/LMP2-transduced autologous dendritic cells may stimulate a specific cytotoxic T-lymphocyte (CTL) response against LMP1- and LMP2-expressing tumor positive cells, resulting in tumor cell lysis and inhibition of tumor cell proliferation.

(Ad5F35-LMP1/LMP2-Transduced Autologous Dendritic Cells, NCI Thesaurus)

Widely expressed by human ADORA3 Gene (GPCR1 Family), 318-aa 36-kDa Adenosine A3 Receptor is a cell-surface integral membrane protein containing 7 transmembrane domains and 3 potential N-glycosylation sites that interacts with a heterotrimeric G protein complex in response to adenosine ligand to suppress cAMP accumulation through adenylate cyclase inhibition.

(Adenosine Receptor A3, NCI Thesaurus)

MEK inhibitor TAK-733 selectively binds to and inhibits the activity of MEK1/2, preventing the activation of MEK1/2-dependent effector proteins and transcription factors, which may result in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation.

(MEK Inhibitor TAK-733, NCI Thesaurus)

TE-AR MAI PUTEA INTERESA