INTRA

Traducere în limba română

intra-state adjectiv

1. în interiorul statului.

2. (amer.) în interiorul unui stat al S.U.A.

Exemple de propoziții și/sau fraze:

Melphalan alkylates DNA at the N7 position of guanine residues and induces DNA intra- and inter-strand cross-linkages.

(Melphalan-Flufenamide Prodrug, NCI Thesaurus)

GPRs contain 7 hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops and transduce a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins.

(G Protein-Coupled Receptor Gene, NCI Thesaurus)

Upon administration, melphalan is converted into highly reactive ethylenimmonium intermediates that induce covalent guanine N7-N7 intra- and inter-crosslinks and alkylation of adenine N3 of DNA; RNA and proteins may also be alkylated.

(Melphalan Hydrochloride/Sulfobutyl Ether Beta-Cyclodextrin Complex, NCI Thesaurus)

Melphalan hydrochloride is converted into highly reactive ethylenimmonium intermediates that induce covalent guanine N7-N7 intra- and inter-crosslinks and alkylation of adenine N3 of DNA.

(Melphalan Hydrochloride, NCI Thesaurus)

The resulting bioactive mono-alkyltriazene species are capable of alkylating nucleophilic residues in the immediate vicinity such as N-7 and/or O-6 sites of guanine, thereby causes intra- or inter-stranded DNA cross-links and trigger apoptosis.

(Mitozolomide, NCI Thesaurus)

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