LEADING

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Traducere în limba română

leading¹ substantiv

material de plumb; obiecte / articole de plumb.

leading² I. adjectiv

1. prim, principal, cel dintâi, important; călăuzitor, conducător;

leading man om important; şef; notabilitate; (mar.) şef de cart; matelot de clasa I;

the leading people in the world of art somităţile din domeniul artei;

leading idea idea dominantă / conducătoare (a unei opere etc.).

2. din faţă / frunte.

3. care mână / conduce.

leading II. substantiv

1. conducere.

2. indicaţie, semn; aluzie.

Exemple de propoziții și/sau fraze:

I am only, of course, giving you the leading results now of my examination of the paper.

(The Memoirs of Sherlock Holmes, de Sir Arthur Conan Doyle)

The window is a long French one, which really forms a door leading to the lawn.

(The Return of Sherlock Holmes, de Sir Arthur Conan Doyle)

I really am ashamed of always leading the way.

(Emma, de Jane Austen)

But here is my sister, sir; here is Fanny, turning and leading her forward; it is so dark you do not see her.

(Mansfield Park, de Jane Austen)

The news results from quiet, confidential talks you conducted leading up to this full moon.

(AstrologyZone.com, de Susan Miller)

“David Copperfield,” said Mrs. Creakle, leading me to a sofa, and sitting down beside me.

(David Copperfield, de Charles Dickens)

Anti-EGFR monoclonal antibody GT-MAB 5.2-GEX specifically binds to the extracellular domain of EGFR, thereby potentially inducing an antibody-dependent cell-mediated cytotoxicity (ADCC) against EGFR-expressing tumor cells, eventually leading to tumor cell apoptosis and an inhibition of tumor cell growth.

(Anti-EGFR Monoclonal Antibody GT-MAB 5.2-GEX, NCI Thesaurus)

In turn, this stimulates calcium ion influx through voltage-gated calcium channels, raising intracellular calcium ion levels and leading to the release of insulin-containing granules The IKATP channels found in pancreatic islets are complexes of four IKATP 6.2 and four SUR1 subunits.

(Meglitinide Antidiabetic Agent, NCI Thesaurus)

Anti-CD20 monoclonal antibody TL011 specifically binds to the B cell-specific cell surface antigen CD20 antigen (MS4A1; membrane-spanning 4-domains, subfamily A, member 1), thereby potentially triggering an immune response against CD20-positive B cells, leading to B cell apoptosis.

(Anti-CD20 Monoclonal Antibody TL011, NCI Thesaurus)

N-(4-methoxyphenyl)retinamide (4-MPR) may activate retinoic acid receptors, thereby altering the expression of certain genes leading to cell differentiation and decreased cell proliferation in susceptible cells. 4-MPR, a major metabolite of fenretinide, may also induce apoptosis through an RAR-independent mechanism that is not yet fully elucidated.

(N-(4-Methoxyphenyl)retinamide, NCI Thesaurus)

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