MACHINERY

Pronunție (USA): (GB):

Traducere în limba română

machinery substantiv

1. utilaj; instalaţii mecanice; instalaţie de exploatare.

2. maşini; parc de maşini.

3. mecanism, părţi de maşină; organ / parte de maşină.

4. (fig.) mecanism, maşinărie, aparat; structură.

5. (fig.) combinaţie (pentru realizarea unui scop).

Exemple de propoziții și/sau fraze:

It interacts with the transcription machinery and nuclear receptor coactivators or corepressors to regulate target gene activity.

(Gene Expression Regulation by Vitamin D Receptor Pathway, NCI Thesaurus/BIOCARTA)

One who is in control of the functioning of a piece of machinery.

(Equipment Operator, NCI Thesaurus)

Nucleotides are assembled into the strands by machinery that includes the enzyme DNA polymerase.

(Structural Snapshots of Damaged DNA, NIH)

Topotecan selectively inhibits topoisomerase I activity by stabilizing topoisomerase I-DNA covalent complexes during the S phase of the cell cycle, thereby inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when encountered by the DNA replication machinery.

(Oral Topotecan Hydrochloride, NCI Thesaurus)

Gimatecan binds to and inhibits the activity of topoisomerase I, stabilizing the cleavable complex of topoisomerase I-DNA, which inhibits the religation of single-stranded DNA breaks generated by topoisomerase I; lethal double-stranded DNA breaks occur when the topoisomerase I-DNA complex is encountered by the DNA replication machinery, DNA replication is disrupted, and the tumor cell undergoes apoptosis.

(Gimatecan, NCI Thesaurus)

During the S phase of the cell cycle, irinotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery.

(liposome-encapsulated irinotecan hydrochloride PEP02, NCI Thesaurus)

Most farm accidents involve machinery.

(Farm Health and Safety, Occupational Safety and Health Administration)

Belotecan binds to and inhibits the activity of topoisomerase I, stabilizing the cleavable complex of topoisomerase I-DNA, which inhibits the religation of single-stranded DNA breaks generated by topoisomerase I; lethal double-stranded DNA breaks occur when the topoisomerase I-DNA complex is encountered by the DNA replication machinery, DNA replication is disrupted, and the tumor cell undergoes apoptosis.

(Belotecan hydrochloride, NCI Thesaurus)

Camptothecin selectively stabilizes topoisomerase I-DNA covalent complexes, thereby inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when encountered by the DNA replication machinery, thus inhibiting DNA replication and triggering apoptotic cell death.

(Camptothecin-20(S)-O-Propionate Hydrate, NCI Thesaurus)

Camptothecin analogue TLC388 selectively stabilizes topoisomerase I-DNA covalent complexes during S-phase, thereby inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when encountered by the DNA replication machinery.

(Camptothecin Analogue TLC388, NCI Thesaurus)

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