METASTASIS

Pronunție (USA): (GB):

Traducere în limba română

metastasis substantiv

1. (med. etc.) metastază.

2. (biol.) metabolism.

Exemple de propoziții și/sau fraze:

When cancer spreads from one part of the body to another in a process called metastasis, it can eventually grow beyond the reach of effective therapies.

(Scientists develop potential new approach to stop cancer metastasis, National Institutes of Health)

This may result in the inhibition of endothelial cell-cell interactions, endothelial cell-matrix interactions, and integrin-mediated tumor angiogenesis and metastasis in alpha5beta1-expressing tumor cells.

(Anti-A5B1 Integrin Monoclonal Antibody PF-04605412, NCI Thesaurus)

The most common sites of metastasis are the lungs, bone, and brain.

(Alveolar soft part sarcoma, NCI Thesaurus)

Metastases are rare.

(Angiomatoid Fibrous Histiocytoma, NCI Thesaurus)

Anti-human integrin alpha v subunit monoclonal antibody EMD 525797, a chimeric antibody which includes the antigen binding sites of the anti-integrin mouse antibody 17E6, binds to and inhibits the activity of alphaVbeta3 integrin (vitronectin receptor); this may result in the inhibition of endothelial cell-cell interactions, endothelial cell-matrix interactions, and integrin-mediated tumor angiogenesis and metastasis in alphavbeta3-expressing tumor cells.

(Anti-alphaVbeta3 Monoclonal Antibody EMD 525797, NCI Thesaurus)

This may cause cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis.

(Anti-c-Met Monoclonal Antibody ABT-700, NCI Thesaurus)

T describes the size of the tumor and any spread of cancer into nearby tissue; N describes spread of cancer to nearby lymph nodes; and M describes metastasis (spread of cancer to other parts of the body).

(AJCC staging system, NCI Dictionary)

This may result in cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis.

(Anti-c-MET Monoclonal Antibody LY2875358, NCI Thesaurus)

CSF1R, also known as macrophage colony-stimulating factor receptor (M-CSFR) and CD115 (Cluster of Differentiation 115), is a cell-surface receptor for its ligand colony stimulating factor 1 (CSF1); this receptor is overexpressed or mutated in certain tumor cell types and plays major roles in tumor cell proliferation and metastasis.

(Anti-CSF1R Monoclonal Antibody IMC-CS4, NCI Thesaurus)

The receptor tyrosine kinase c-Met, also known as hepatocyte growth factor (HGF) receptor, is overexpressed or mutated in many tumor cell types, playing an important role in tumor cell proliferation, survival, invasion, and metastasis and angiogenesis.

(MET Tyrosine Kinase Inhibitor PF-04217903, NCI Thesaurus)

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