MODIFY

Pronunție (USA): (GB):

Traducere în limba română

modify verb tranzitiv

1. a modifica, a schimba (parţial); a atenua; a inmuia.

2. (lingv.) a schimba prin apofonie/ prin alternanţă vocalică.

Exemple de propoziții și/sau fraze:

Increased expression of these proteins by this autologous cell line may activate an antitumor T-cell response when the modified cells are administered to the patient.

(ALVAC-hB7.1, NCI Thesaurus)

Scientists can then create genetically modified animals in which only a specific set of neurons contains the receptor.

(Controlling Brain Circuits in Mice, NIH)

As to your suggestion that I may modify my opinion, I would have you know that it is not my habit to do so after a deliberate expression of my mature views.

(The Lost World, de Sir Arthur Conan Doyle)

Allogeneic melanoma vaccine AGI-101H consists of a 1:1 mixture of cells from two genetically modified human melanoma cell lines, designated as Mich1H6 and Mich2H6, that have been gamma-irradiated to render the cells non-proliferative.

(Allogeneic Melanoma Vaccine AGI-101H, NCI Thesaurus)

Endothelial cell-specific transcriptional control of the adenoviral vector is achieved by the use of a modified murine PPE-1 promoter that is specifically activated in PPE-1-expressing angiogenic endothelial cells residing in the tumor microvasculature.

(Angiogenesis Inhibitor GT-111, NCI Thesaurus)

A preparation of autologous peripheral blood T-lymphocytes (PBTL) that have been genetically modified to express a chimeric antigen receptor (CAR) consisting of an anti-CD19 scFv (single chain variable fragment) coupled to the costimulatory signaling domain CD28 and the zeta chain of the T-cell receptor (TCR)/CD3 complex (CD3 zeta), with potential immunostimulating and antineoplastic activities.

(Anti-CD19-CAR Retroviral Vector-Transduced Autologous T Cells, NCI Thesaurus)

Upon infusion, allogeneic CD19-specific CAR-modified CD8+ central memory-derived virus-specific T cells directs the T-lymphocytes to CD19-expressing tumor cells, stimulating a selective toxicity to tumor cells which may eventually result in tumor cell lysis.

(Allogeneic CD19-specific CAR-modified CD8 Plus Central Memory-derived Virus-specific T Cells, NCI Thesaurus)

An allogeneic melanoma cell vaccine derived from a cell line with high expression of melanoma associated antigens and genetically modified to express both HLA-A2 and 4-1BB ligand, with potential immunostimulating and antineoplastic activities.

(Allogeneic HLA-A2/4-1BB ligand-expressing Melanoma Vaccine, NCI Thesaurus)

These include being part of a molecular pathway connected to tau that, in the absence of sufficient NO, can modify tau protein in a way that causes it to clump together to form aggregates.

(Pathogenic tau and cognitive impairment are precipitated by a high-salt diet, National Institutes of Health)

Upon transfection of donor T-lymphocytes with a plasmid encoding a fusion protein of the IL13-zetakine and the selection-suicide expression enzyme HyTK, these modified CTLs are expanded and introduced into a patient with glioblastoma multiforme (GBM).

(Allogeneic IL13-Zetakine/HyTK-Expressing-Glucocorticoid Resistant Cytotoxic T Lymphocytes GRm13Z40-2, NCI Thesaurus)

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