PROGENITOR

Pronunție (USA): (GB):

Traducere în limba română

progenitor substantiv

1. strămoş, străbun, bunic;

(fam.) our progenitors autorii zilelor noastre, cei ce ne-au făcut.

2. (fig.) predecesor, precursor, înaintaş.

Exemple de propoziții și/sau fraze:

One of the two stem cells derived from HEMATOPOIETIC STEM CELLS - the other being the lymphoid progenitor cell.

(Bone Marrow Myeloid Stem Cell, NLM, Medical Subject Headings)

When blood cells become old or damaged and die, progenitor cells produce new blood cells to take their place.

(An overlooked role for lungs in blood formation, NIH)

An ETS-domain transcription factor essential for the development of myeloid (osteoclast progenitors) and B-lymphoid cells.

(Oncogene SPI1, NCI Thesaurus)

The research provides evidence for a substantially revised roadmap for normal blood regeneration or blood production in the natural environment; and highlights how in those conditions blood stem cells and progenitor cells manifest unique properties.

(Cellular barcoding helps scientists understand the behavior of stem cells, National Institutes of Health)

Expressed in lung, liver, skeletal muscle, bone marrow, placenta, pancreas, and fetal liver by human CCL23 Gene (Intercrine Beta Family), secreted immunoregulatory Small Inducible Cytokine A23 Isoform Ckbeta8 is a potent CCR1 receptor agonist and suppressor of progenitor cell colony formation with chemotactic activity for resting T lymphocytes, monocytes, and neutrophils in inflammatory processes.

(C-C Motif Chemokine 23, NCI Thesaurus)

The AKR strain is also a source of the Thy1.1 thymocyte antigen, which is expressed on thymocyte, bone marrow and T cell progenitors and is used as a marker for a variety of stem cells.

(AKR/J Mouse, NCI Thesaurus)

Suppression of c-myb expression with this agent may result in the restoration of normal differentiation pathways, increased antiproliferative effects, and the induction of apoptosis in early progenitor hematopoietic cells and in tumor cells that overexpress c-myb.

(C-myb Antisense Oligonucleotide G4460, NCI Thesaurus)

A tumor progenitor cell.

(Clonogen, NCI Thesaurus)

Human MYB Oncogene Protein is a product of a mutated variant (Oncogene MYB) of MYB Gene, which encodes 6 alternative isoforms of 640 aa 72-kDa nuclear c-MYB protein, a DNA-binding transcriptional activator critical for hematopoietic progenitor cell proliferation and differentiation.

(Myb Oncogene Protein, NCI Thesaurus)

By performing a series of lung transplants between mice with certain deficiencies, the team discovered that blood cell progenitors were able to migrate out of the lung and into the bone marrow, where they could completely restore production of platelets and other blood cells.

(An overlooked role for lungs in blood formation, NIH)

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