REARRANGEMENT

Pronunție (USA): (GB):

Traducere în limba română

rearrangement substantiv

rearanjare, aranjare din nou, aranjament nou.

Exemple de propoziții și/sau fraze:

This rearrangement results in the formation of the BCR-ABL1 fusion protein.

(BCR-ABL1 Fusion Protein Expression, NCI Thesaurus)

This rearrangement is associated with acute myeloid leukemia and myelodysplastic syndrome.

(CBFB/MYH11 Fusion Gene, NCI Thesaurus)

Characterized by clonal T-cell receptor gene rearrangement.

(Angioimmunoblastic Lymphadenopathy, NCI Thesaurus/PDQ)

This rearrangement is associated with aberrant expression of the LCP1 gene product and non-Hodgkin follicular lymphoma and Burkitt lymphoma.

(BCL6/LCP1 Fusion Gene, NCI Thesaurus)

ALK is not expressed in healthy adult human tissue but ALK dysregulation and gene rearrangements are associated with a series of tumors; ALK mutations are associated with acquired resistance to small molecule tyrosine kinase inhibitors.

(ALK Inhibitor X-396, NCI Thesaurus)

While cancer drugs induce formation of TOP2-DPCs to treat cancer, TOP2-DPC lesions can also be the source of disease, as they can cause rearrangement of an organism’s genome that leads to cancer.

(DNA damage caused by cancer treatment reversed by ZATT protein, National Institutes of Health)

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