SUBSEQUENT

Pronunție (USA): (GB):

Traducere în limba română

subsequent adjectiv

(to) care urmează (după) sau (cu dat.), următor, posterior;

subsequent to his death după moartea sa;

subsequent reinforcement (mil.) completarea rândurilor din rezervele spatelui armatei.

Exemple de propoziții și/sau fraze:

Subsequent tests showed that the rat retina also remained functional.

(Researchers develop “hibernation in a dish” to study how animals adapt to the cold, National Institutes of Health)

The original gamma camera invented by H. O. Anger in 1957 and its subsequent generations.

(Anger Camera, NCI Thesaurus)

Beta-amyloid fragments are derived from proteolytic processing of amyloid precursor protein (APP) in neurons, and the subsequent release of fragments into the extracellular space.

(Amyloid Beta-Peptide Pathway, NCI Thesaurus/BIOCARTA)

It is further characterized by an inflammatory reaction of the glomerular capillaries due to the proliferation of mesangial cells, expansion of the mesangial matrix and deposition of immune complexes causing subsequent thickening of the glomerular basement membrane.

(Nephrotic Syndrome with Lesion of Membranoproliferative Glomerulonephritis, NCI Thesaurus)

In the kidney, inhibition of the beta-2 receptor within the juxtaglomerular apparatus results in the inhibition of renin production and a subsequent reduction in angiotensin II and aldosterone levels, thus inhibiting angiotensin II-dependent vasoconstriction and aldosterone-dependent water retention.

(Nadolol, NCI Thesaurus)

Upon vaccination with p.DOM-WT1-37 DNA and subsequent electroporation, this vaccine may induce a WT1 epitope-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing cancer cells.

(p.DOM-WT1-37 DNA Vaccine, NCI Thesaurus)

Upon vaccination with p.DOM-WT1-126 DNA and subsequent electroporation, this vaccine may induce a WT1 epitope-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing cancer cells.

(p.DOM-WT1-126 DNA Vaccine, NCI Thesaurus)

MoAb ABT-806 targets the EGFR deletion variant, de2-7 EGFR as well as wild-type EGFR expressed in cells overexpressing the receptor, thereby preventing the activation and subsequent dimerization of the receptor; the decrease in receptor activation and dimerization result in an inhibition in signal transduction and anti-proliferative effects.

(Anti-EGFR Monoclonal Antibody ABT-806, NCI Thesaurus)

Anti-IGF-1R recombinant monoclonal antibody BIIB022 binds to membrane-bound IGF-1R, preventing binding of the ligand IGF-1 and the subsequent triggering of the PI3K/Akt signaling pathway; inhibition of this survival signaling pathway may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.

(Anti-IGF-1R Recombinant Monoclonal Antibody BIIB022, NCI Thesaurus)

Anti-IGF-1R monoclonal antibody AVE1642 specifically binds to and blocks membrane-bound IGF-1R, preventing the binding of the natural ligand IGF-1 and the subsequent activation of PI3K/AKT signal transduction, which may result in the induction of apoptosis and a decrease in cellular proliferation.

(Anti-IGF-1R Monoclonal Antibody AVE1642, NCI Thesaurus)

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