SUBSEQUENTLY

Pronunție (USA): (GB):

Traducere în limba română

subsequently adverb

pe urmă, după aceea, mai târziu, ulterior.

Exemple de propoziții și/sau fraze:

With Mars in your sign, you will be in control and ready to announce a big decision and to subsequently take bold action.

(AstrologyZone.com, de Susan Miller)

Noscapine binds to tubulin and alters its conformation, resulting in a disruption of the dynamics of microtubule assembly (by increasing the time that microtubules spend idle in a paused state) and subsequently, the inhibition of mitosis and tumor cell death.

(Noscapine Hydrochloride, NCI Thesaurus)

Pan-AKT kinase inhibitor GSK-690693 binds to and inhibits Akt kinases 1, 2, and 3, which may result in the inhibition of protein phosphorylation events downstream from Akt kinases in the PI3K/Akt signaling pathway, and, subsequently, the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.

(Pan-AKT Kinase Inhibitor GSK690693, NCI Thesaurus)

Muromonab-CD3 binds to and inhibits CD3 on the surface of circulating T-lymphocytes; binding of muromonab-CD3 to CD3-positive T cells results in an early activation of this T cell subset, followed by cytokine release, and subsequently inhibition of T cell functions.

(muromonab-CD3, NCI Thesaurus)

Subsequently, the Fas-c (Fas-chimeric) death receptor, containing Fas and tumor necrosis factor (TNF) receptor 1 (TNFR1) moieties, is expressed in angiogenic endothelial cells; endothelial cell-specific Fas-mediated apoptosis is initiated by the binding of TNF-alpha, abundant in the tumor microenvironment, to the TNFR1 moiety of the expressed Fas-c death receptor.

(Angiogenesis Inhibitor GT-111, NCI Thesaurus)

Subsequently, aminoflavone is metabolized to toxic metabolites by the cytochromome P450 enzymes that it induces; these toxic metabolites covalently bind to DNA, resulting in the phosphorylation of p53, the induction of the p53 downstream target p21Waf1/Cip1, and apoptosis.

(AFP464, NCI Thesaurus)

Upon cell entry and release from the polymer-metal complex, cisplatin forms highly reactive, charged platinum complexes that bind to nucleophilic groups such as GC-rich sites in DNA, inducing intrastrand and interstrand DNA cross-linking, DNA-protein cross-linking and, subsequently, tumor cell apoptosis and growth inhibition.

(Micellar Nanoparticle-Encapsulated Cisplatin NC-6004, NCI Thesaurus)

Subsequently, the Fc component of the engineered antibody targets and binds to the CD64 receptor on the dendritic cells (DCs); upon processing by DCs, the cellular immune system may be activated to induce helper T-cell and CTL immune responses against tumor cells expressing the TRP2 antigen.

(Melanoma TRP2 CTL Epitope Vaccine SCIB1, NCI Thesaurus)

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