SURVIVAL

Pronunție (USA): (GB):

Traducere în limba română

survival substantiv

1. supravieţuire.

2. rămăşiţă (a unui vechi obicei etc.).

Exemple de propoziții și/sau fraze:

However, chemotherapy carries the risk of severe early side effects, which can reduce chances of survival.

(Early treatment benefits infants with severe combined immunodeficiency, NIH)

Amphibians can acquire immunological resistance that overcomes chytrid-induced immunosuppression and increases survival.

(Amphibians can acquire resistance to deadly fungus, NSF)

It classifies patients into five groups with significantly different disease-free and overall survival and grades pathological remission in both the primary tumor and the axillary lymph nodes, with comparison of negative nodes with those that have already responded to chemotherapy.

(Miller and Payne Classification, NCI Thesaurus)

Anti-HGF monoclonal antibody TAK-701 binds to the soluble ligand HGF, preventing HGF binding to and activation of the HGF receptor c-Met and so the activation of the c-Met signaling pathway; this may result in the induction of cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase overexpressed or mutated in a variety of tumor cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis.

(Anti-HGF Monoclonal Antibody TAK-701, NCI Thesaurus)

This may result in cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis.

(Anti-c-MET Monoclonal Antibody LY2875358, NCI Thesaurus)

A protein that helps control several cell functions, including cell division and survival, and binds to rapamycin and other drugs. mTOR may be more active in some types of cancer cells than it is in normal cells.

(mTOR, NCI Dictionary)

An inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine kinase activity of mTOR, resulting in decreased expression of mRNAs necessary for cell cycle progression, which may induce cell cycle arrest and tumor cell apoptosis. mTOR phosphorylates transcription factors, such as S6K1 and 4E-BP1, which stimulate protein synthesis and regulate cell growth, proliferation, motility, and survival.

(mTOR Kinase Inhibitor AZD8055, NCI Thesaurus)

Integrins are cellular adhesion molecules (CAMs) that are upregulated in various types of cancer and some autoimmune diseases; alpha4beta1 integrin (VLA4) has been implicated in the survival of myeloma cells, possibly by mediating their adhesion to stromal cells.

(Natalizumab, NCI Thesaurus)

A group established in 1969 with goals: to improve the survival of children with Wilms tumor and other renal tumors, to study the long-term outcome of children treated successfully by identifying adverse effects of treatment, to study the epidemiology and biology of Wilms tumor and to make information regarding successful treatment strategies for Wilms tumor available to physicians around the world.

(National Wilms' Tumor Study Group, NCI Thesaurus)

An orally bioavailable small-molecule inhibitor of p38 and Tie2 kinases with potential antineoplastic, anti-inflammatory and antiangiogenic activities. p38/Tie2 kinase inhibitor Arry-614 binds to and inhibits the activities of p38 and Tie2 kinases, which may inhibit the production of proinflammatory cytokines and may decrease tumor angiogenesis and tumor cell growth and survival. p38 is a MAP kinase that is often upregulated in cancer cells, playing a crucial part in the production of a variety of cytokines involved in inflammation and cellular proliferation such as tumor necrosis factor (TNF) and interleukin (IL)-1 and -6.

(Multikinase Inhibitor ARRY614, NCI Thesaurus)

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