SUSCEPTIBLE

Pronunție (USA): (GB):

Traducere în limba română

susceptible adjectiv

1. susceptibil.

2. sensibil, impresionabil.

3. posibil, care permite, care îngăduie;

susceptible of proof susceptibil de a fi dovedit.

4. predispus (la o boală etc.).

Exemple de propoziții și/sau fraze:

He was no longer susceptible to pain.

(Love of Life and Other Stories, de Jack London)

We found that it is possible to use brain scans to detect which patients are highly susceptible to the more aggressive forms of multiple sclerosis.

(Smoldering spots in the brain may signal severe multiple sclerosis, National Institutes of Health)

The Aquarians most susceptible to the possible problems with the October 27 new noon and conditions in the last week of October and early November were those born on or within five days of January 24.

(AstrologyZone.com, de Susan Miller)

PI3K inhibitor GDC-0941 selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway; inhibition of tumor cell growth, motility and survival in susceptible tumor cell populations may result.

(PI3K Inhibitor GDC-0941 Bismesylate, NCI Thesaurus)

Class 1 PI3K kinase family inhibitor XL147 reversibly binds to class 1 PI3Ks in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K signaling pathway; this may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations.

(PI3K Family Kinase Inhibitor XL147, NCI Thesaurus)

Farnesyltransferase inhibitor BMS-214662 inhibits the enzyme farnesyltransferase and the post-translational farnesylation of number of proteins involved in signal transduction, which may result in the inhibition of Ras function and apoptosis in susceptible tumor cells.

(BMS-214662, NCI Thesaurus)

Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.

(Midostaurin, NCI Thesaurus)

N-(4-methoxyphenyl)retinamide (4-MPR) may activate retinoic acid receptors, thereby altering the expression of certain genes leading to cell differentiation and decreased cell proliferation in susceptible cells. 4-MPR, a major metabolite of fenretinide, may also induce apoptosis through an RAR-independent mechanism that is not yet fully elucidated.

(N-(4-Methoxyphenyl)retinamide, NCI Thesaurus)

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