THEREBY

Pronunție (USA): (GB):

Traducere în limba română

thereby (înainte de un verb; la sfârşitul unei propoziţii) adverb

1. prin aceasta; din aceasta; cu aceasta; de aici; astfel, în acest chip, drept urmare;

thereby you may lose prin aceasta poţi să pierzi.

2. (înv.dial.) pe aproape, în apropiere, în vecinătate, la doi paşi;

she lives thereby locuieşte pe aproape.

3. (înv.) în legătură cu aceasta, despre aceasta;

thereby hangs a tale şi asta nu e tot, e poveste întreagă, e (o poveste) cu cântec.

Exemple de propoziții și/sau fraze:

Ah, thereby hangs a rather painful tale.

(The Adventures of Sherlock Holmes, de Sir Arthur Conan Doyle)

Meluadrine binds to and activates beta-2 adrenergic receptors of myometrial smooth muscle in the uterus, thereby activates adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP).

(Meluadrine, NCI Thesaurus)

Memantine binds to and inhibits cation channels of glutamanergic NMDA receptors located in the central nervous system (CNS), preventing the prolonged influx of calcium ions and the associated neuronal excitotoxicity, and thereby potentially enhancing cognitive function.

(Memantine hydrochloride, NCI Thesaurus)

Catherine had never thought on the subject till that moment, but, upon examining her purse, was convinced that but for this kindness of her friend, she might have been turned from the house without even the means of getting home; and the distress in which she must have been thereby involved filling the minds of both, scarcely another word was said by either during the time of their remaining together.

(Northanger Abbey, de Jane Austen)

Akt inhibitor LY2780301 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway, thereby leading to inhibition of cell proliferation and the induction of apoptosis in tumor cells.

(Akt Inhibitor LY2780301, NCI Thesaurus)

What we found using different tumor models is that if you treat mice with antibiotics and thereby deplete certain bacteria, you can change the composition of immune cells of the liver, affecting tumor growth in the liver, said Tim Greten, M.D., of NCI’s CCR, who led the study.

(Study finds gut microbiome can control antitumor immune function in liver, National Institutes of Health)

These agents display potent antitumor properties due to their ability to intercalate into DNA and interfere with the function of both the topoisomerase I and II enzymes, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis.

(Aclacinomycin Antitumor Antibiotic, NCI Thesaurus)

The study suggests that these newly-termed ‘simulation neurons’ – found in the amygdala, a collection of nerve cells in the temporal lobe of the brain – allow animals (and potentially also humans) to reconstruct their social partner’s state of mind and thereby predict their intentions.

(‘Mindreading’ neurons simulate decisions of social partners, University of Cambridge)

MEK inhibitor WX-554 selectively binds to and inhibits the activity of MEK, thereby preventing the activation of MEK-dependent effector proteins including some transcription factors, which may result in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation.

(MEK Inhibitor WX-554, NCI Thesaurus)

We then did further studies, and found that if we treat mice with bile acids, we can actually change the number of NKT cells in the liver, and thereby the number of tumors in the liver.

(Study finds gut microbiome can control antitumor immune function in liver, National Institutes of Health)

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