VECTOR

Pronunție (USA): (GB):

Traducere în limba română

vector substantiv

1. (mat.) vector.

2. (med.) agent (de contaminare), purtător (al unei maladii).

Exemple de propoziții și/sau fraze:

A cancer vaccine consisting of a recombinant adenoviral vector encoding the tumor-associated antigen (TAA) human MUC-1 (hMUC-1) linked to the extracellular domain (ecd) of the co-stimulatory molecule CD40 ligand (CD40L) and an adenovirus signal sequence that encodes a secretory signal peptide (Ad-sig) with potential immunostimulating and antineoplastic activities.

(Ad-sig-hMUC-1/ecdCD40L Vaccine, NCI Thesaurus)

A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a recombinant adenoviral vector encoding three full length human melanoma associated antigens (MAAs), tyrosinase, melan-A (MART-1) and the melanoma antigen A6 (MAGEA6), with potential antineoplastic activity.

(Adenovirus Encoding Tyrosinase/MART-1/MAGEA6-transduced Autologous Dendritic Cell Vaccine, NCI Thesaurus)

Allogeneic CMV/AdV-specific cytotoxic T lymphocytes are prepared by exposing donor-derived CTLs to a lethally irradiated Epstein-Barr virus-positive lymphoblastoid B cell line (EBV-LCL) that has been transduced with a clinical-grade adenoviral vector (Ad5f35CMVpp65) as a source of CMV and AdV antigens.

(Allogeneic CMV/AdV-Specific Cytotoxic T Lymphocytes, NCI Thesaurus)

CD34+ peripheral blood stem cells (PBSC) isolated from patient with hematopoietic cell tumor, and transfected with murine stem cell virus retroviral vector encoding a mutant version of the human DNA repair protein O6-alkylguanine-DNA methyltransferase (MGMT).

(MSCV (MGMTP140K) Retroviral Vector-Transduced CD34+ Autologous PBSC, NCI Thesaurus)

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